Adverse events of sacral neuromodulation for fecal incontinence reported to the federal drug administration

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Adverse events of sacral neuromodulation for fecal incontinence reported to the federal drug administration.

AIM To investigate the nature and severity of AE related to sacral neurostimulation (SNS). METHODS Based on Pubmed and Embase searches, we identified published trials and case series of SNS for fecal incontinence (FI) and extracted data on adverse events, requiring an active intervention. Those problems were operationally defined as infection, device removal explant or need for lead and/or ge...

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Sacral neuromodulation for the treatment of fecal incontinence: analysis of cost-effectiveness.

PURPOSE The cost-effectiveness and budget impact of introducing sacral nerve modulation (SNM) as a treatment for fecal incontinence in Italy were evaluated in a simulation model. METHODS A decision-analysis model with a Markov submodel was used to represent clinical pathways for treatment of patients with fecal incontinence in a scenario with SNM and a scenario without SNM. Data were obtained...

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Serious adverse drug events reported to the Food and Drug Administration, 1998-2005.

BACKGROUND The US Food and Drug Administration has operated the Adverse Event Reporting System since 1998. It collects all voluntary reports of adverse drug events submitted directly to the agency or through drug manufacturers. METHODS Using extracts published for research use, we analyzed all serious adverse drug events and medication errors in the United States reported to the Food and Drug...

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Sacral nerve stimulation for fecal incontinence.

Fecal incontinence (FI), which can severely affect a person's quality of life, is a difficult problem to treat. For some patients, limited management options exist. Sacral nerve stimulation, also known as sacral neuromodulation, although long established for urinary incontinence, has gained acceptance in treating FI. One unique aspect is that the procedure is performed in two stages. During the...

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Sacral nerve stimulation for fecal incontinence

Objective: to analyze short-term outcomes and complications for our first fifty patients with fecal incontinence undergoing sacral root stimulation. Patients: fifty patients with fecal incontinence receiving sacral neuromodulation in 4 hospitals are reviewed. Discussed variables include: age, sex, incontinence duration, incontinence cause, prior surgery for incontinence, Wexner scale score, ano...

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ژورنال

عنوان ژورنال: World Journal of Gastrointestinal Pharmacology and Therapeutics

سال: 2016

ISSN: 2150-5349

DOI: 10.4292/wjgpt.v7.i2.294